Introducing highly fermentable prebiotics into a gut that is currently overgrown with pathogenic or histamine-producing bacteria can trigger a "flare-up." The harmful bacteria will rapidly ferment the new fiber, producing excess gas, LPS, and histamine, which can temporarily worsen leaky gut and provoke a severe mast cell reaction
That said, whey protein can have some adverse reactions for certain people
Horie, I
Typical medication side effects generally improve within several weeks as tolerance develops, whereas colitis symptoms often worsen or persist without treatment
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Ozempic and Adderall each have their own risks, including side effects and contraindications
