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It binds copper(II) with high affinity, and the copper complex not the bare peptide is the biologically active species

10.1016/j.expneurol.2022.114171 Exp

Consequently, it is preferred by many of the medical directors with whom we work as a means of providing metabolic assistance without causing the traditional side effects such as heart palpitations and jitters seen with stimulants containing caffeine, (e.g., sympathomimetic drugs)

Peptides degrade when exposed to incorrect temperatures or light

Duration depends on your goals: postinjury or postsurgery protocols might last 816 weeks, while chronic wearandtear cases may benefit from longer courses with periodic reassessment