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Two Phase 2 trials were conducted concurrently: one in adults with obesity without diabetes, published in the New England Journal of Medicine in June 2023, and one in adults with type 2 diabetes, published simultaneously in The Lancet

Semaglutide belongs to a class of drugs called glucagon-like peptide-1 (GLP-1) receptor agonists

The mechanism of action is the same as GLP-1, including stimulation of insulin secretion, slowing gastric emptying, and reducing postprandial glucagon secretion in a glucose-dependent fashion

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Hormones, menopause, and brain resilience Hormones are not the whole dementia story, but they are part of the physiologic landscape

Feb 3, 2026 You have the vial in your hand