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Safety, tolerability, and pharmacodynamics of intrathecal injection of recombinant human HGF (KP-100) in subjects with amyotrophic lateral sclerosis: a Phase I trial

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PMID: 17643602

This includes reduced rates of acute decompensated liver failure and alcoholic hepatitis, although, notably, no significant difference was observed in the progression to cirrhosis within the study period (Wickramarachchi et al., 2025)