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Through the website JASPAR ( we observed that, among the peaks near the TSS in GCLC, a sequence was highly homologous to the NRF2-binding motif (Fig

Both semaglutide (a GLP-1 receptor agonist) and tirzepatide (which targets both GLP-1 and GIP receptors) work by regulating appetite, improving blood sugar control, and helping the body feel fuller with less food

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Phagocytic cells, through oxidative stress, are involved in tissue and organ damage [20]

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One targets hormonal satiety signals while the other suppresses the central nervous systems hunger response