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In clinical trials studying Wegovy (2.4 mg), the average weight loss was 15% and 20%, respectively, when paired with diet and exercise (compared to 2.4% and 3.1% with diet and exercise alone)

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Again, the complications were hypoglycaemia and, with the 1.8 mg dose, ketosis

Velmurugan K, Balamurugan AN, Loganathan G, Ahmad A, Hering BJ, Pugazhenthi S

Nutritional deficiencies resulting from reduced food intake could theoretically contribute to glossitis (tongue inflammation), particularly in patients also taking metformin, which can reduce vitamin B12 absorption

Research-grade Tesamorelin peptide is a separate category, available for laboratory research under research-use-only terms without prescription