One limitation of our study is the absence of a lean/pair-fed Bbs5 / group, which could have clarified whether the observed effects in ciliopathies are secondary to obesity
Speak to your prescriber before combining any weight loss treatments
For instance, individuals with prediabetes or metabolic syndrome could benefit from early intervention
With tirzepatide dose escalation extending to 15mg and semaglutide to 2.4mg weekly, clinicians in 2025-2026 have increasingly noted that reduced food intake at higher doses can compound electrolyte losses particularly sodium and magnesium which are direct headache triggers
Back pain is one of the most common health complaints worldwide, affecting an estimated 619 million people globally
It could represent a new treatment option for AUD, particularly for those who have not benefited from existing medications, and may reduce alcohol-related health and social harms