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We show that the heterogeneity in mitochondrial function and signalling observed across CRC samples could explain, and be used to predict, poor clinical responses in patients with locally advanced CRC

Some patients may experience improvements in sexual function, while others may notice no change or even temporary decreases due to factors such as caloric restriction, fatigue during the adjustment period, or gastrointestinal side effects that affect overall well-being

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10.1104/pp.107.4.1139 41 DudlerR.HertigC.RebmannG.BullJ.MauchF

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