It incorporates N-terminal acetylation and C-terminal amidation for enhanced proteolytic stability in research settings
Cardiac Electrophysiology : In a randomized, placebo-controlled crossover study, 79 healthy subjects were administered a single oral dose of JANUVIA 100 mg, JANUVIA 800 mg (8 times the recommended dose), and placebo
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In the case of neuropathic or nociplastic pain, pharmacologic options include the use of lidocaine patches and topical capsaicin