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biologic therapy initiation Severe/fulminant: IV corticosteroids (methylprednisolone 4060 mg/day IV)

Step 3: Push the plunger in to add 10 mL of air to the vial and then draw out 10 mL of bacteriostatic water by slowly pulling the plunger back out

Strict process controls ensure reproducibility, allowing researchers to work with confidence across experiments

What are the risks or possible complications

Summary: Vitamin B12 supplements can occasionally cause mild stomach side effects including nausea, diarrhoea, abdominal cramping, and indigestion, though these are generally uncommon and temporary

Hematologic and biochemical monitoring throughout the trials revealed no concerning patterns in blood counts, liver function tests, kidney function markers, or other laboratory parameters