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2018;43(1):e12571
an HMGCR-independent pathway, including allosteric hindrance of lymphocyte function-associated antigen 1 (LFA-1), which represses activation, proliferation, and cellular migration of T cells [40] and HMGCR-dependent mechanisms, which rely on their ability to prevent prenylation of small GTPases [41, 42]
This surprises people who have read about it in the context of fat loss and assumed it would work the same way GLP-1 medications do
IGF-1 stands for insulin-like growth factor 1, a hormone that regulates growth hormone levels
Gambioli R, Montanino Oliva M, Nordio M, Chiefari A, Puliani G, Unfer V