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Non-Oxidative Reactions of the PPP The non-oxidative reactions of the PPP are primarily designed to generate ribose-5-phosphate (R5P)

WEHI, 32D (32Dcl3), WT, T315I-BcrAbl-transformed 32D, and TCCS cells were maintained in RPMI 1640 medium (Sigma) supplemented with 10% heat-inactivated FBS, 1% Streptomycin/Penicillin, 1 mM sodium pyruvate, and 10 mM HEPES

Data availability The RNA-seq data generated in this study has been deposited in the Gene Expression Omnibus (GEO) database at NCBI under accession code GSE249592

Supports Healthy Cell Function and Healthy Aging

Beyond its role as an antioxidant, it acts as a cellular recycler

Such studies would have important implications for understanding whether oxidative stress in migraine preferentially affects regions involved in trigeminal nociception and central pain processing, or reflects a more generalized metabolic vulnerability