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CARDIOVASCULAR EFFECTS OF GLP-1 RAs IN HUMAN STUDIES Blood pressure and heart rate Circulating biomarkers and lipid profiles Carotid intima-media thickness LV function and reperfusion injury in patients with coronary artery disease Retrospective studies on cardiovascular outcomes A prospective randomized clinical trial with primary cardiovascular outcome: the ELIXA study Preclinical and preliminary clinical evidence has consistently revealed potential cardiovascular benefits from the administration of GLP-1 RAs

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Most are gastrointestinal, tend to be mild to moderate, and often improve as your body adjusts and as the dose is increased slowly

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Apolipoprotein E (APOE) is a key lipid-transporting protein primarily involved in cholesterol and phospholipid metabolism in both peripheral tissues and the central nervous system

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