Currently, GPx3 is considered a new tumor-suppressor gene [23], and its hypermethylation, which is associated with the further down-regulation of GPx3, was observed in patients with Barretts esophagus [54], endometrial adenocarcinoma [55] and prostate cancer [56]
Furthermore, exogenous GSH influences intracellular GSH levels through the glutamyl- cycle, which plays a critical role in promoting early embryonic development in cattle []
The concentrations of GSH in animal cells are in the range of 500-10,000 M [27,28]
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Rice ascorbate peroxidase gene family encodes functionally diverse isoforms localized in different sub cellular compartments