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[1] [2] Wegovy is also approved for weight management in pediatric patients aged 12 years and older with obesity, and for cardiovascular risk reduction in adults with established cardiovascular disease and either obesity or overweight
At the highest tested dose of 12mg administered once weekly, participants lost an average of 24.2% of their body weight
Soliqua Solostar combines insulin glargine with lixisenatide, a GLP-1 receptor agonist, to help control blood glucose in adults with type 2 diabetes
The trial randomised 2,339 adults with obesity (or overweight with a weight-related comorbidity) and without type 2 diabetes to retatrutide 4mg, 9mg, or 12mg weekly (titrated upward from 2mg in four-weekly steps) or placebo
doi:10.3390/ijms22158199
12 weeks 6-9 vials ~84 daily doses
