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Here, we found that the neuronal conditional-knockout (KO) of glutamyl-cysteine-ligase catalytic-subunit (GCLC), a rate-limiting enzyme for glutathione synthesis, induced brain atrophy accompanied by neuronal loss and neuroinflammation

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Participants applied the lotion to one half of their faces for 10 weeks

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Third, these compounds often exhibit poor stability, degrading quickly under physiological conditions, which reduces their efficacy