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However, another combination of filters turned out to be the most suitable when applying ANN modeling (wavelet denoise spectral smoothing, asymmetric least square baseline correction, standard normal variate normalization, and quadratic first derivate)

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Patients with sluggish response (less than 0.5% weekly weight loss despite caloric deficit) increase to 1.5ml weekly or add a second injection mid-week at 0.51ml

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