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JOSEPH SCHACHT: Thats a great question

the compound's evidence base is limited to preclinical in vitro and animal (largely rodent) studies of IGF-1 receptor activation, muscle-cell signaling, and tissue repair, with human safety and efficacy data for this specific analog effectively absent

Indeed, as we have observed in case 6, the diagnosis of Wernicke Encephalopathy was ignored because of the patients non-alcoholic background

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10.3892/ijmm.2021.5052 Int

Potent body weight loss, and therapeutic efficacy in a NASH animal model by a novel long-acting GLP-1/Glucagon/GIP tri-agonist (HM15211)