AC demonstrated significant anticonvulsant activity in the PTZ model, with no effect in the MES and NMDA models
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Mechanisms of disease: hydrogen peroxide, DNA damage and mutagenesis in the development of thyroid tumors
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However, CMS clarified in a memo dated March 20, 2024, that anti-obesity medications that receive FDA approval for an additional medically accepted indication can be considered a Part D drug for that specific use. As of August 19, 2024, the only GLP-1 RA this applies to is Wegovy, which, in addition to its obesity indication, is also indicated to reduce the risk of major adverse cardiovascular events in adults with established cardiovascular disease and either obesity or overweight
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