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Human studies Only one observational study investigated the effect of polyphenol supplementation on ES-induced behavior

Semaglutide remains a first-line choice due to longer clinical experience, lower initial cost (especially compounded versions), and well-characterized side effect profiles

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Zoccali C, Curatola G, Panuccio V, Tripepi R, Pizzini P, Versace M,

Savings programs and pharmacy benefit managers like GoodRx can sometimes offer discounts, reducing out-of-pocket expenses

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