This year, when she was ready to take a GLP-1 again following a pregnancy, the drug was no longer covered for weight loss
Those who take significantly more may experience serious side effects like a painful erection, kidney dysfunction, body aches, and sweating
Also, they are not an extension of any other brand or manufacturer
Consequently, GLP-1 analogs are used for treatment of T2D and the GLP-1 analogs liraglutide and, more recently, semaglutide have been approved by the Food and Drug Administration to support weight loss in obesity (Trapp & Brierley, 2022)
Contrastingly, their latest phase III multicentre UK trial for exenatide in 194 people with mild to moderate PD (exenatide-PD3) has only recently been completed and found no difference between drug and placebo over 2 years, suggesting that this medication may not have disease-modifying potential in this group of patients.81 The pharmacologically akin GLP-1RA lixisenatide has recently been investigated in a key phase II randomised placebo-controlled trial (LIXIPARK) involving 156 people with early PD in France: an improvement in motor symptoms only on the MDS-UPDRS part 3 was found at 12 months (MD 3.08
GLP-1 receptor agonists directly modify a persons diet and change how tolerable some foods are, so its possible that contributes to the effect
