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The Role of Body Metabolism Your metabolism and lifestyle also play a role in how much you might need
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Metabolic health, insulin resistance patterns, family history of obesity, and genetic variations affecting appetite regulation and glucose metabolism all influence whether GLP-1 therapy may be appropriate and how your body might respond to treatment
However, efficacy in clinical studies has been disappointing, possibly because excessive chronic stimulation is associated with receptor internalisation, and some agents have disturbed liver function [25, 26]
Further research is warranted to elucidate the underlying mechanisms and optimize therapeutic strategies when these medications are used together
Kernan WN, Viscoli CM, Furie KL, Young LH, Inzucchi SE, Gorman M, et al
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