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The use of molecular docking and spectroscopic methods for investigation of the interaction between regorafenib with human serum albumin (HSA) and calf thymus DNA (ct-DNA) in the presence of different site markers

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DSIP is an amphiphilic peptide of molecular weight 850 daltons with the amino acid motif:N-Trp-Ala-Gly-Gly-Asp-Ala-Ser-Gly-Glu-C It has been found in both free and bound forms in the hypothalamus, limbic system and pituitary as well as various peripheral organs, tissues and body fluids.[5] In the pituitary it co-localises with many peptide and non-peptide mediators such as corticotropin-like intermediate peptide (CLIP), adrenocorticotrophic hormone (ACTH), melanocyte-stimulating hormone (MSH), thyroid-stimulating hormone (TSH) and melanin concentrating hormone (MCH)

Sauzet O, Carvajal A, Escudero A, Molokhia M, Cornelius VR