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Inborn errors of metabolism (e.g., vitamin B6-dependent convulsions or B6-responsive anemia)

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Sterile water earns its place in single-session use cases and for individuals with benzyl alcohol sensitivity, but its the exception rather than the rule

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poor nutrition or vegan diet) Transcobalamin II deficiency It is also used as part of the vitamin B12 absorption test (Schilling test)

In the withdrawal trial, participants switched to placebo regained about 14% over the following year. Tapering, at least 1.2 g/kg of protein, resistance training, and follow-up reduce the risk, but no post-stop protocol guarantees maintenance