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[1] Exposure to elevated temperatures can denature the peptide structure, potentially reducing effectiveness or altering the safety profile

Second, study populations have been heterogeneous with respect to diabetes status, obesity, renal function, baseline cardiovascular disease, and HF phenotype, which may limit generalizability

Sigma 1 receptor co-localizes with NRF2 in retinal photoreceptor cells

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We note that a conformer 2-like state was not previously observed for the GLP-1-bound receptor complex using the same method for 3D variability analysis