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Folate Why it matters: Folate (vitamin B9) works closely with vitamin B12 in critical metabolic pathways

This blockage results in increased glycogen synthesis which, by increasing our reserves, produces the feeling of satiety

coli host is unknown

Similar to blood-brain barrier but some structural differences

Furthermore, heterogeneity in tumour stage (or indeed, location), patient populations and treatment dose and duration is likely to confound reported response data, particularly given the links between changes in oxidative metabolism and metastatic spread 84,85,86,87

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