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Using a genetically engineered mouse model, the researchers demonstrated that newer small-molecule GLP-1 drugssuch as recently approved oral medicationscan reach deep brain regions

Firstly, dont stop your GLP-1 medication without speaking to your prescribing doctor

Mechanistically, studies indicate that the transition from hyperoxia back to normoxia paradoxically suppresses FAO while promoting ceramide synthesis, both pathways converging to promote apoptosis

Having more options available to patients is a good thing, says Daniel Drucker, an endocrinologist at the University of Toronto whose research paved the way for GLP-1 drugs but who was not involved in the new studies

There are a handful of reasons: 1) Obesity : 1 in 8 is obese worldwide, doubled since 1990 2) Usage : increasing into apnea, kidney and heart health, in testing for cancer & addiction 3) Ease : pills will bring down costs and increase usage 4) Innovation : new drugs bring greater weight loss, fewer side effects and unique action 5) Cost : pills, generics, subsidies, insurance and increased competitors all drive price down Q: Is GLP-1 a trend that is likely to stay or is the bubble about to burst