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Although relative risk estimates varied slightly across studies, absolute event rates remained very low in all groups
Joseph, F., Anderson, L., Goenka, N
The role of mitochondria in amyotrophic lateral sclerosis
In contrast, more contemporary studies, including Barrett et al
Because of this pleiotropic effect, distinguishing between direct, i.e., via agonist-receptor interaction, and indirect effects of these agonists in vivo is challenging
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