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Multiple ANOVA testing revealed five proteins significantly increased in abundance in ALS compared to HCs in both visits, including chitotriosidase-1 (CHIT1), CHI3L1 (chitinase-3-like protein 1), CHI3L2 (chitinase-3-like protein 2), COL18A1 (collagen alpha-1(XVIII) chain) and FCGR3A (low affinity immunoglobulin gamma Fc region receptor III-A)