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R COMT uses Mg2+ to coordinate the catechol hydroxyl groups and position the substrate for selective methylation at the meta or para position

Under the control treatment all the mutants, especially zir1 , nrc1 and nrc2 , showed reduced growth compared to the WT (Fig

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In one study published in Molecular Psychiatry, researchers examined mice exposed to prolonged stress, finding structural changes in the amygdala, the part of the brain known to regulate emotions, including fear and anxiety