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The picture is complicated by the presence of additional MDHA- and DHA-reducing systems, in addition to the enzymes encoded by the genes shown in Table 1

Hardie LJ, Briggs JA, Davidson LA, Allan JM, King RF, Williams GI, Wild CP

[8] Although not an absolute contraindication, patients with coronary artery disease or unstable angina should only use B-Complex injections containing niacinamide under physician supervision, since high-dose niacin supplements have been linked to arrhythmias in such patients

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