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The results are dependent on many factors and vary from person to person

A recent study showed that TMAO induces osteogenic responses in human aortic valve interstitial cells via ERmitochondrial stress in vitro and aggravates aortic valve lesions in mice (72)

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Interestingly, systolic and diastolic blood pressure, as well as LDL-cholesterol levels were found to be significantly reduced after 6 months of Pycnogenol supplementation, compared to placebo

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