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The body makes its own choline, but levels can drop with age, toxic exposures, or chronic illness

A systematic review and meta-analysis of 37 randomized controlled trials found that levocarnitine supplementation produced modest but statistically significant reductions in body weight, BMI, and fat mass, particularly among adults with overweight or obesity

They also think that we all need the same measly amount regardless of our symptoms and level of damage

Semin Neurol

Sex balance is another dimension where our present studies fail to be representative

Documented case reports exist for serotonin syndrome when combining MAOIs with serotonin precursors like 5-HTP, and the mechanism applies to serotonergic neuropeptides like P21 or Cerebrolysin