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doses 0.25-8 mg) and 4-week multiple-ascending dose (MAD

2016 Feb 29;25(1):79-84

Only 7% report discontinuing within one month or less of starting, and nearly all (97%) report discontinuation within the first year

Semaglutide was associated with gastrointestinal adverse events (nausea, vomiting, diarrhea, constipation) which were of mild to moderate severity, short duration, and resolved without treatment discontinuation ( Notably, a recent systematic review showed that compared to other semaglutide doses and GLP-1 RAs, 2.4 mg semaglutide had the greatest effect on weight reduction, controlling glucose level, and reducing BP

Obesity can cause various health issues

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