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This leads to dryness of the ocular and oral mucosa (xerophthalmia and xerostomia), along with possible involvement of the pharynx, larynx, and vagina ( Furthermore, SS can also be complicated by severe manifestations such as multiorgan involvement and hematologic malignancies ( When SS affects a previously healthy individual, it is defined primary SS (pSS)

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Details and References: Coffee melanoidins may act as soluble fiber enhancing immune-stimulating properties and contributing significantly to reducing the risk of colon cancer (Vitaglione, 2012

The researchers point out that GLP-1RAs are expensive and can potentially widen health disparities as obesity disproportionately affects marginalized racial, ethnic and socioeconomic communities

Future studies in real-world settings may prove beneficial in gauging the efficacy of semaglutide more realistically

This is firmly in the territory of working closely with a clinician and following a structured protocol