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PPAR- agonists inhibit NF-B activation and suppress the JAK/STAT pathway to reduce the expression and release of IL-1, IL-6, IL-8, and TNF-, thereby exerting anti-inflammatory effects (119)

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doi: 10.1155/2013/956792 221 PolonikovA

These findings represent some of the strongest evidence that a peptide compound can meaningfully modulate telomere biology in human cells

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