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Clinical trials conducted in the early 2000s showed modest results, and the compound failed to demonstrate sufficient efficacy to support regulatory approval as a weight-loss medicine

If symptoms persist despite regular oral supplementation, absorption may be limited

The recommended daily intake of niacin for lactation is ~17-20 mg, which is easily met by a normal diet

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When treating vitamin B12 deficiency, Hydroxocobalamin 20 mg/ml Injection Solution is usually administered as a single intramuscular or intravenous injection, followed by monthly injections for up to 6 months

For individuals following a plant-based or vegetarian diet, B12 IM injections may be a preferred method of supplementation, as plant foods do not naturally contain significant amounts of B12