The potential of GLP-1RAs to induce psychiatric adverse events is biologically plausible given the widespread expression of GLP-1 receptors in the central nervous system, 167 their influence on neurocognitive function, 168 and their effects on inflammation, stress response, and energy metabolism, which theoretically could improve mood
Sequence your food: Starting meals with fiber and protein before carbohydrates has been shown to produce a greater GLP-1 response in some studies and lower post-meal glucose levels
This is particularly significant for individuals with type 2 diabetes, who often face heightened risks of cardiovascular complications
Ozempic and Trulicity are also used to lower the risk of heart attack and stroke in adults with type 2 diabetes and heart disease
Retatrutide is the International Nonproprietary Name (INN) assigned by the WHO, and LY3437943 is the development code used by Eli Lilly in clinical trials and scientific publications
The mediation analysis indicated that weight loss explained 68% of the systolic and 71% of the diastolic blood pressure reduction