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Dehkordi AH, Abbaszadeh A, Mir S, Hasanvand A
Medical Director * The evidence comes from STEP UP, a 72-week clinical trial in adults with a BMI of 27 or above using Wegovy (semaglutide 7.2mg)
Ive finally found something that works and Ive lost over 120 pounds
Restarting without gradually titrating the dose can increase the chance of side effects
A 48-week Phase 2 trial reported in The Lancet in 2025 showed mean weight reduction ranging from approximately 9% at the lowest dose to 20% at the highest dose, compared with 0.4% on placebo
Free radicals also deplete glutathione levels, increasing free radical damage and creating oxidative stress
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