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Biochemistry 31 , 92889293 (1992)

T3-containing medications can also temporarily alter TSH levels

Some discontinued clinical trials (for example in postoperative ileus) failed to demonstrate sufficient efficacy in primary endpoints, although certain biological signaling effects remained measurable and scientifically relevant

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Although venous disease more often produces heaviness, swelling, and varicose veins, it can also coexist with a cold or tight feeling due to localized changes in tissue perfusion and nerve irritation