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Research has shown that when Gpx4 is conditionally knocked out in the kidney or liver, it can lead to spontaneous ferroptotic damage [58, 205]
Brain Res 1049 : 171181
SUMOylation contributes to cellular resistance to oxidative stress and regulates antioxidant gene expression by enhancing NRF2 stability and activity [130]
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In the Flinders University study, of the 6954 women first prescribed GLP-1 receptor agonists during 2022, 90.5% did not have type 2 diabetes, suggesting that many were using the medication for weight loss
125 At the molecular level, aging leads to the downregulation of key transcription factors such as EOMES and T-bet, hindering NK cell maturation
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