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Hepatic gluconeogenesis and insulin sensitivity were improved in ob/ob mice treated with recombinant adenovirus expressing GLP-1 (rAd-GLP-1) [22]
Farilla L, Bulotta A, Hirshberg B, et al
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The third the key duration-extending modification attaches a C18 fatty diacid chain to lysine at position 26, via a mini-PEG spacer
Their mechanism is completely independent of the HPTA
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