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The hepatocyte growth factor/c-met signaling pathway as a therapeutic target to inhibit angiogenesis

Time-to-onset analysis of NAEs associated with GLP-1 RAs The median time-to-onset of NAEs for all GLP-1 RAs was 31 days (interquartile range [IQR] 7123), with 46.25% occurring within the first 30 days of treatment initiation (Table S6, Figure S2)

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The evidence base consists primarily of animal studies with limited human clinical data