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The lipid modification makes retatrutide micelle-prone in solution and repeated freeze-thaw is the most common cause of activity loss

Even at high summer temperatures, the peptides in lyophilized form are stable for several weeks

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Reversal by Exendin-4 treatment

Each vial contains sterile water for injection with 0.9% benzyl alcohol, which acts as a bacteriostatic preservative inhibiting microbial growth so the vial can be used for multiple draws over time