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The international or national clinical trial registries, including the ClinicalTrials.gov, European Union Clinical Trials Register, World Health Organization-International Clinical Trials Registry Platform and 9 national clinical trial registries were also searched

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Increased Heart Rate : Feeling your heart racing or pounding at rest

Severe persistent nausea requires dose holds or slower escalationcontact your provider immediately rather than adjusting doses independently

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In 2016, the International Agency for Research on Cancer published a consensus on the strength of evidence for cancer types that are directly affected by excess body adiposity