A metastasis-prone signature for early-stage mismatch-repair proficient sporadic colorectal cancer patients and its implications for possible therapeutics
Despite early interest, it has not progressed through formal clinical development and remains a research compound
Response from the owner: Thank you Micheal
Introducing our 1st student resident for 2026: Lucero Ramos, a first year Physician Assistant student from Augsburg University in Minneapolis
Downregulation or deficiency of pyruvate kinase leads to ATP depletion which in turn affects cell viability as well as accumulation of the glycolytic intermediates (2,3-diphosphoglycerate (2,3-DPG) that eventually leads to impaired glycolytic flux 46
Song JX, An JR, Chen Q, Yang XY, Jia CL, Xu S, et al