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In septic mice, semaglutide attenuated sickness behavior, hypothermia, systemic inflammation, and lung injury through the downregulation of pro-inflammatory cytokines (TNF- , IL-1, IL-6, CXCL1), suppression of neutrophil infiltration, and decreased expression of genes associated with tissue remodeling and inflammation (Mmp9, Timp1, Ly6g)
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Guthenberg C, Warholm M, Rane A, Mannervik B
However, a 2021 Cochrane review found that across 18 studies and 1,945 participants, weight loss over 12 to 13 weeks in groups that took green tea extract was not much more significant than groups that did not take it
This may include other medication classes such as SGLT2 inhibitors, DPP-4 inhibitors, or insulin therapy, depending on your individual circumstances and treatment goals
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