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Glutathione oxidation in response to intracellular H 2 O 2 : key but overlapping roles for dehydroascorbate reductases

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TDP-43 is an important pathological protein because the abnormal accumulation of misfolded, wildtype (WT) cytoplasmic TDP-43 into inclusions is the characteristic pathological hallmark of ~97% of ALS patients (sALS and fALS

Huang H, Liu N, Guo H, Liao S, Li X, Yang C, et al

Those enrolled in the study all had reasonable control determined by mean insulin growth factor (IGF-1) levels in the previous year (median -0.3, range -2.72.2 ng/ml), with no differences between the GHD and ISS patients

But metformin can also affect vitamin B12 absorption, she says