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Mechanisms include: Restoration of endothelial nitric oxide synthase (eNOS) Upregulation of VEGF and FGF-2 (fibroblast growth factor 2) Reduction of oxidative stress and cytokine-induced apoptosis BPC-157 preserved endothelium-dependent vasodilation via upregulation of eNOS and suppression of vascular inflammation. Gwyer Findlay et al., Peptides 4

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Brain microvascular endothelial cells express five carriers for the amino acid alanine belonging to two groups, neutral amino acid transporters (ASCT/SLC1A) or small neutral amino acid transporters (SNAT/SLC38A)

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