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Nanoparticles labeled with a mUNO peptide (CSPGAK), which is a CD206-binding peptide, promote selective drug delivery to M2-type TAMs and induce M2 to M1 reprogramming of the macrophage phenotype 33

Also, there are nerves in the gut which can sense GLP-1 and signal back to the brain, so the picture is a lot more complicated and more research is being carried out into the way GLP-1 and GLP-1 mimetics work

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